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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-9-17
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pubmed:abstractText |
Changes in cell volume and 42K+ efflux associated with concentrative alanine uptake were studied in isolated rat hepatocytes suspended in Krebs-Ringer bicarbonate buffer. After addition of 10 mM-alanine, cellular water volume increased by 15% and the rate constant of 42K+ efflux by 250%. Alanine-induced 42K+ efflux was abolished by quinine and was strongly decreased when the cell-volume increase was counteracted by sucrose. The results suggest that K+ efflux during alanine uptake is implicated in a volume-regulatory response.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-5112657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-5576764,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6154702,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6273550,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6427469,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6641937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6754947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6808083,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6834422,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6846545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-6849920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-7034548,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-7069788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-7175489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-7407122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6466316-970270
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
221
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
265-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6466316-Alanine,
pubmed-meshheading:6466316-Animals,
pubmed-meshheading:6466316-Apamin,
pubmed-meshheading:6466316-Body Water,
pubmed-meshheading:6466316-Female,
pubmed-meshheading:6466316-Furosemide,
pubmed-meshheading:6466316-Liver,
pubmed-meshheading:6466316-Potassium,
pubmed-meshheading:6466316-Quinine,
pubmed-meshheading:6466316-Rats,
pubmed-meshheading:6466316-Rats, Inbred Strains,
pubmed-meshheading:6466316-Sucrose
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pubmed:year |
1984
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pubmed:articleTitle |
Volume-regulatory K+ efflux during concentrative uptake of alanine in isolated rat hepatocytes.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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