Linked Life Data

6465001

Source:http://linkedlifedata.com/resource/pubmed/id/6465001

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1984-8-29
pubmed:abstractText
To determine the effects of intravenous thrombolytic therapy on the development of left ventricular (LV) thrombi after anterior acute myocardial infarction (MI), 22 consecutive patients were prospectively studied with radionuclide ventriculography and serial 2-dimensional echocardiography: 12 patients who presented within 3 hours after MI received intravenous streptokinase (STK) followed by intravenous heparin as thrombolytic treatment and 10 patients who were seen later than 3 hours after the onset of symptoms served as controls. The LV ejection fraction was less than 0.40 in 3 of 12 patients who received STK and in 7 of 10 who did not (control subjects) (p less than 0.05). Apical dyssynergy was observed in all 12 patients treated with STK and in 9 of 10 control subjects. LV thrombi were presented within 36 hours of MI in 5 control subjects. Thrombi were detected by 2-dimensional echocardiography in 7 of 10 control subjects and in 1 of 12 patients who received intravenous STK (p less than 0.005). Early thrombolytic therapy with intravenous STK and heparin appears to significantly reduce the frequency of LV thrombus formation despite persistence of apical dyssynergy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
54
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-3
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of early systemic thrombolytic therapy on left ventricular mural thrombus formation in acute anterior myocardial infarction.
pubmed:publicationType
Journal Article