Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1984-9-13
|
| pubmed:abstractText |
The effects of T-2 toxin on bacterial infection and leukocyte function and structure were examined in vivo and in vitro. Rats were innoculated with staphylococci after pretreatment with or without T-2 toxin. The T-2 pretreated rats failed to mount a cellular response to the bacteria. Blood and bone marrow cells were markedly suppressed by the T-2 toxin, the myeloid series being the most affected. In vitro studies with human leukocytes showed that small, nonkilling doses of T-2 toxin inhibited chemotaxis, chemiluminescence stimulated by bacteria, and phagocytosis of bacteria. It was concluded that this inhibition may contribute towards sepsis and rapid onset of death in T-2 toxin poisoning.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0041-008X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
75
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
60-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:6464023-Animals,
pubmed-meshheading:6464023-Blood,
pubmed-meshheading:6464023-Bone Marrow,
pubmed-meshheading:6464023-Chemotaxis,
pubmed-meshheading:6464023-Humans,
pubmed-meshheading:6464023-Leukocyte Count,
pubmed-meshheading:6464023-Leukocytes,
pubmed-meshheading:6464023-Male,
pubmed-meshheading:6464023-Phagocytosis,
pubmed-meshheading:6464023-Rats,
pubmed-meshheading:6464023-Sesquiterpenes,
pubmed-meshheading:6464023-Staphylococcal Infections,
pubmed-meshheading:6464023-T-2 Toxin
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
T-2 toxin effect on bacterial infection and leukocyte functions.
|
| pubmed:publicationType |
Journal Article
|