Linked Life Data

6462958

Source:http://linkedlifedata.com/resource/pubmed/id/6462958

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-9-10
pubmed:abstractText
The regional distribution of imipramine (IMI) and desipramine (DMI) in rat brain after single and chronic oral administration of IMI was studied. The distribution of IMI and DMI in all examined brain regions was similar, except for hippocampus + septum. After chronic administration of IMI the disappearance of the parent drug and its metabolite was slowing down in all investigated brain regions as well as in the plasma. The accumulation of IMI and DMI after chronic treatment of IMI was significantly higher in plasma than in all examined brain regions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-0244
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
21-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
The distribution of imipramine and desipramine in rat brain regions after single and chronic administration of imipramine.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't