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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5 Pt 2
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pubmed:dateCreated |
1984-9-19
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pubmed:abstractText |
In vitro antibacterial activity of cefamandole-fosfomycin (CFM-FOS) combination was studied on 50 methicillin-resistant staphylococci strains. Anti-bacterial effects were evaluated with a bactericidal microtiter checkerboard method. CFM-FOS was compared with other combinations known to be potent against staphylococci. Synergy was consistently recorded with CFM-FOS. Mean MBC of CFM combined with FOS was 1 microgram/ml. Vancomycin-fosfomycin combination was infrequently synergistic (20%). Rifampin-fosfomycin, cefamandole-fusidic acid, and cloxacillin-fusidic acid combinations were usually antagonistic at bactericidal levels. Rifampicin-fusidic acid combination usually yielded additive effects. CFM-FOS killed most methicillin-resistant staphylococci studied at therapeutic concentrations.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Cefamandole,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Fosfomycin,
http://linkedlifedata.com/resource/pubmed/chemical/Methicillin
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0369-8114
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
32
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
528-31
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6462742-Anti-Bacterial Agents,
pubmed-meshheading:6462742-Blood Bactericidal Activity,
pubmed-meshheading:6462742-Cefamandole,
pubmed-meshheading:6462742-Drug Combinations,
pubmed-meshheading:6462742-Drug Synergism,
pubmed-meshheading:6462742-Fosfomycin,
pubmed-meshheading:6462742-Methicillin,
pubmed-meshheading:6462742-Microbial Sensitivity Tests,
pubmed-meshheading:6462742-Penicillin Resistance,
pubmed-meshheading:6462742-Staphylococcus
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pubmed:year |
1984
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pubmed:articleTitle |
[In vitro study of the cefamandole-fosfomycin combination against methicillin-resistant staphylococci].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|