Linked Life Data

6455522

Source:http://linkedlifedata.com/resource/pubmed/id/6455522

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-10-29
pubmed:abstractText
In vitro interaction of autologous peripheral blood and synovial fluid lymphocytes was studied using isolated lymphocytes from 15 patients with rheumatoid arthritis. In the applied one way mixed lymphocyte cultures (MLC) a significant proliferative response was obtained when peripheral blood lymphocytes were cultured with mitomycin treated synovial fluid cells. In contrast, when the reverse situation was examined, only a marginal stimulation of synovial fluid lymphocytes by peripheral blood lymphocytes was recorded. Studies on the effect of macrophage depletion on the autologous MLC made in unlikely that the decreased proliferative response of SFL was due to the presence of a monocyte suppressor cell population in SFL. Likewise no evidence could be obtained that the decreased MLC response of SFL to autologous and allogeneic lymphocytes was caused by the predominance of short lived T-suppressor cells in the synovial fluid.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0141-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
27-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Autologous and allogeneic MLC-reactivity in patients with rheumatoid arthritis.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't