Linked Life Data

6454324

Source:http://linkedlifedata.com/resource/pubmed/id/6454324

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-8-10
pubmed:abstractText
Activation of plasminogen to plasmin in uterine fluid results in the formation of plasmin-alpha 2-antiplasmin complexes. The degree of plasminogen activation was studied during the menstrual cycle in IUD-users and nonusers. The absence of free plasminogen in the presence of plasmin complexes indicated complete activation of the zymogen. The simultaneous occurrence of free plasminogen and plasmin complexes were interpreted to represent incomplete activation. Results were correlated with the concentration of alpha 2-antiplasmin, a major inhibitor of urokinase and plasmin. In the midcycle phase of IUD-non-users, plasminogen activation was complete and the concentration of alpha 2-antiplasmin was low. In the luteal phase of the same population the concentration of alpha 2-antiplasmin was high and there was no plasminogen activation. In contrast, IUD-users generally had an incomplete activation of plasminogen throughout the menstrual cycle. Also, their concentrations of alpha 2-antiplasmin were increased in the proliferative and midcycle phases.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-6349
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-101
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Cyclic variation of plasminogen activation in human uterine fluid and the influence of an intrauterine device.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't