Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1981-5-26
|
| pubmed:abstractText |
Regioselective syntheses of substituted 2-chloroquinoxalines and derived 2-(1-piperazinyl)quinoxalines are described. Selectivity in regards to serotonin reuptake blocking and serotoninmimetic activities of the piperazinylquinoxalines is reported. In general, introduction of a 6-substituent into the piperazinylquinoxaline enhanced serotonin reuptake blocking activity and diminished serotoninmimetic activity. Unsubstituted and 3-hydroxypiperazinylquinoxalines had primarily serotoninmimetic activity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0022-2623
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
24
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
93-101
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:6451700-Animals,
pubmed-meshheading:6451700-Chemical Phenomena,
pubmed-meshheading:6451700-Chemistry,
pubmed-meshheading:6451700-Male,
pubmed-meshheading:6451700-Methamphetamine,
pubmed-meshheading:6451700-Neurons,
pubmed-meshheading:6451700-Piperazines,
pubmed-meshheading:6451700-Quinoxalines,
pubmed-meshheading:6451700-Rats,
pubmed-meshheading:6451700-Serotonin
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Piperazinylquinoxalines with central serotoninmimetic activity.
|
| pubmed:publicationType |
Journal Article
|