Linked Life Data

6451172

Source:http://linkedlifedata.com/resource/pubmed/id/6451172

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1981-4-13
pubmed:abstractText
Spontaneous diabetes is a common occurrence in many animal species. In addition, animals can be rendered diabetic by a wide variety of experimental procedures. Diabetic animals may be regarded as models of the disease in man. However, such animals display a wide diversity of pathophysiology, and, in fact, no animal syndrome corresponds precisely to any type of diabetes in human subjects. The most common diabetes syndromes in animals occur in the context of obesity, hyperinsulinemia and insulin resistance. Many such syndromes remit spontaneously. Dietary restriction and weight reduction effectively reverse some of these syndromes, but in other cases only partial correction of the syndrome occurs. Diabetes in lean animals is less common. The diabetes of lean animals is more frequently characterized by hypoinsulinemia, ketosis and insulin dependence than is the case with obese animals. Diabetes may be produced experimentally by means of surgery, viral infection or the administration of various hormones and chemical agents. Both the spontaneous and experimental animal models have been used effectively to study the etiologies, complications, treatments and prevention of diabetes.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9343
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-60
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Animal models of diabetes.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.