Linked Life Data

6450559

Source:http://linkedlifedata.com/resource/pubmed/id/6450559

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1981-3-24
pubmed:abstractText
During a 60-h period after the onset of either the adult respiratory distress syndrome (ARDS) in 14 patients, or similar predisposing conditions without respiratory insufficiency (non-ARDS) in 12 patients, blood was obtained 3 times for assessment of coagulation, fibrinolysis, and complement. Platelet counts decreased progressively in both groups, and a platelet release protein, Beta-thromboglobulin, was similarly increased in both groups. Fibrinopeptide A concentrations were similarly increased in both groups. Hemolytic activity of complement components C3 and C5 was within the normal range in both groups. In contrast, the fibrin/fibrinogen degradation product, D-antigen, was significantly increased in the ARDS group over all time periods (p < 0.01). These findings suggested that higher concentrations of circulating fibrin/fibrinogen degradation products are associated with ARDS itself, either as a marker or more extensive microvascular injury or as a possible mediator of injury.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
122
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
841-7
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Elevated fibrin(ogen) degradation products in the adult respiratory distress syndrome.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.