Linked Life Data

6444243

Source:http://linkedlifedata.com/resource/pubmed/id/6444243

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5742
pubmed:dateCreated
1980-2-26
pubmed:abstractText
The synthesis of RNA catalysed by RNA polymerase from Escherichia coli is terminated at specific sites on DNA templates through the action of a multimeric basic protein known as rho (refs 1, 2). Three lines of evidence suggest that an interactions of rho with the nascent RNA is important for this termination. First, rho binds strongly to RNA; second, rho expresses an RNA-dependent ATPase activity which is essential for termination; third, RNA polymerase does not terminate RNA synthesis at rho-dependent sites when the nascent RNA is digested by ribonuclease during transcription. From the fact that certain RNAs, particularly single-stranded, pyrimidine-rich polymers containing at least 10% cytidylate residues, are more effective than other RNAs at promoting rho-ATPase, it has been proposed that rho recognises specific sites oion on a mRNA transcribed from bacteriophage lambda DNA.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
283
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
102-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
A rho-recognition site on phage lambda cro-gene mRNA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.