rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
1985-3-26
|
pubmed:abstractText |
As shown by means of Ouchterlony double immunodiffusion technique after induction with 3-methyl cholanthrene the antibodies towards cytochrome P-448 from rat liver tissue developed a clear-cut precipitation line with homologous antigen and interacted also with cytochrome P-448 from mice liver tissue although the precipitation was less distinct. Antibodies towards mice liver cytochrome P-448 reacted also with the rat liver cytochrome P-448 but less distinctly as compared with the mice cytochrome. At the same time, these antibodies inhibited similarly the benz(a)-pyrene-hydroxylase reaction, catalyzed by both mice and rat cytochromes P-448. Partial immunological identity appears to occur in the cytochromes studied. Role of total antigenic determinants in enzymatic reactions catalyzed by cytochrome P-448 is discussed.
|
pubmed:language |
rus
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0042-8809
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
98-102
|
pubmed:dateRevised |
2009-11-19
|
pubmed:meshHeading |
pubmed-meshheading:6442038-Animals,
pubmed-meshheading:6442038-Benzo(a)pyrene,
pubmed-meshheading:6442038-Chemical Precipitation,
pubmed-meshheading:6442038-Cytochrome P-450 Enzyme System,
pubmed-meshheading:6442038-Cytochromes,
pubmed-meshheading:6442038-Enzyme Induction,
pubmed-meshheading:6442038-Immunodiffusion,
pubmed-meshheading:6442038-Isoenzymes,
pubmed-meshheading:6442038-Male,
pubmed-meshheading:6442038-Methylcholanthrene,
pubmed-meshheading:6442038-Mice,
pubmed-meshheading:6442038-Mice, Inbred C57BL,
pubmed-meshheading:6442038-Microsomes, Liver,
pubmed-meshheading:6442038-Rats,
pubmed-meshheading:6442038-Rats, Inbred Strains
|
pubmed:articleTitle |
[Immunological study of the identity of cytochrome P-448 in the mouse and rat liver after induction with 3-methylcholanthrene].
|
pubmed:publicationType |
Journal Article,
English Abstract
|