Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-4-9
pubmed:abstractText
Dermatosparaxis is an inherited disease which results from a deficiency in procollagen aminopropeptidase activity. A form of this disease in sheep has been examined which is much milder than the previously reported instance in sheep. Partially processed pN alpha 1 and pN alpha 2 chains are present in the skin of affected animals and have been characterized by gel electrophoresis, amino acid analysis, susceptibility to collagenase digestions and by segment-long-spacing aggregate formations. Fully processed collagen is also present in the skin of affected animals indicating that some aminopropeptidase activity is present. Extracts from the skin of affected animals were shown to contain an aminopropeptidase activity which was about 25% of the activity found in similar extracts from normal animals.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0174-173X
pubmed:author
pubmed:issnType
Print
pubmed:volume
4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
441-51
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
A mild form of ovine dermatosparaxis.
pubmed:publicationType
Journal Article