|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1985-2-11
|
|
pubmed:abstractText |
Imipenem (formerly N-formimidoyl thienamycin) and ceftazidime were investigated for their postantibiotic effect on Pseudomonas aeruginosa. Four strains of P. aeruginosa in the logarithmic phase of growth were exposed for 1 and 2 h to concentrations of antibiotics achievable in human serum. Recovery periods of test cultures were evaluated after dilution or addition of beta-lactamase. A consistent postantibiotic effect against all strains was obtained with imipenem but not with ceftazidime. Although ceftazidime did not have a postantibiotic effect, it did suppress the growth of the organisms at concentrations equivalent to one-third of the MIC. The clinical implications of these effects need further evaluation.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-16561067,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-16561549,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-16561809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-217866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-369783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-45147,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-4959982,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-6213594,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-6583199,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-6784225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-6792299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-792494,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6440477-839090
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0066-4804
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
26
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
678-82
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1984
|
|
pubmed:articleTitle |
Postantibiotic effect of imipenem on Pseudomonas aeruginosa.
|
|
pubmed:publicationType |
Journal Article
|
