Linked Life Data

6438521

Source:http://linkedlifedata.com/resource/pubmed/id/6438521

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5991
pubmed:dateCreated
1984-12-24
pubmed:abstractText
The myc gene seems to have a causal role in tumour formation in man, mouse and avian systems. The myc gene product has been localized to the nucleus, suggesting that it may be involved in the regulation of gene expression. The level of expression of the mammalian heat shock protein 70 (HSP70) gene is elevated in several tumour cell lines, implying that a cellular function expressed in these tumour lines can stimulate HSP70 production. We report here that the gene product of a rearranged mouse c-myc gene is capable of stimulating expression of chimaeric genes containing a Drosophila hsp70 promoter region and 5'-flanking sequences. This stimulation is dependent on sequences located more than 200 bases 5' of the normal start of hsp70 transcription.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0028-0836
pubmed:author
pubmed:issnType
Print
pubmed:volume
312
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
280-2
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Regulation of heat shock protein 70 gene expression by c-myc.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't