Linked Life Data

6437385

Source:http://linkedlifedata.com/resource/pubmed/id/6437385

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1984-12-5
pubmed:abstractText
Responses of isolated intestinal preparations from the anurans Bufo marinus and Limnodynastes tasmaniensis to various agents have been studied, as models for the intestinal stasis reported in the rare gastric brooding frog, Rheobatrachus silus. It is inferred from the responses that the preparations possessed excitatory muscarinic and histamine receptors and inhibitory adrenergic receptors, conforming to the typical vertebrate pattern. The circular muscle was unresponsive to prostaglandin E2, whereas longitudinal muscle relaxed to prostaglandin E2. Some of the longitudinal preparations exhibited a biphasic response to arachidonic acid, i.e. contraction followed by relaxation. Indomethacin prevented the relaxation phase, indicating that the intestine synthesised a prostaglandin E-like substance from arachidonic acid. These results draw attention to the possibility that PGE2 may be responsible for the intestinal stasis associated with gastric brooding in the gastric brooding frog.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0004-945X
pubmed:author
pubmed:issnType
Print
pubmed:volume
62 ( Pt 3)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
317-23
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
On the possible role of prostaglandin E2 in intestinal stasis in the gastric brooding frog Rheobatrachus silus.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, Non-U.S. Gov't