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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1984-12-18
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pubmed:abstractText |
Patients who received transfusions and nontransfused control patients were followed to assess the incidence and cause of post-transfusion hepatitis and to identify donor factors that might relate to risk of hepatitis. We evaluated as risk factors in donors the presence of antibody to hepatitis B virus compared with elevated alanine aminotransferase (ALT) level. Units of blood that were positive for antibody to hepatitis B core antigen (anti-HBc) were associated with a twofold to threefold greater risk of non-A, non-B hepatitis in the recipients than were units without anti-HBc. In the absence of specific serologic tests for non-A, non-B agents, screening of donors for anti-HBc might be considered. Our data suggest that the incidence of non-A, non-B hepatitis might have been reduced by about one third by such screening. However, elevated ALT levels in donors had a similar association with non-A, non-B hepatitis in recipients but would have resulted in fewer units of blood being discarded than would screening for anti-HBc.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alanine Transaminase,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B Antibodies,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B Core Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Hepatitis B Surface Antigens
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-4819
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
733-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6437308-Alanine Transaminase,
pubmed-meshheading:6437308-Blood Donors,
pubmed-meshheading:6437308-Blood Transfusion,
pubmed-meshheading:6437308-Hepatitis, Viral, Human,
pubmed-meshheading:6437308-Hepatitis B Antibodies,
pubmed-meshheading:6437308-Hepatitis B Core Antigens,
pubmed-meshheading:6437308-Hepatitis B Surface Antigens,
pubmed-meshheading:6437308-Hepatitis C,
pubmed-meshheading:6437308-Humans,
pubmed-meshheading:6437308-Risk,
pubmed-meshheading:6437308-United States
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pubmed:year |
1984
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pubmed:articleTitle |
Hepatitis B virus antibody in blood donors and the occurrence of non-A, non-B hepatitis in transfusion recipients. An analysis of the Transfusion-Transmitted Viruses Study.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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