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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-11-30
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pubmed:abstractText |
The clinical, haematological and biosynthetic features of subjects with Hb E variants are described. An association with red cell hypochromia and microcytosis was confirmed, although this was not invariable in Hb E trait. Imbalanced globin chain synthesis was found in the majority of Hb E carriers. A patient doubly heterozygous for Hb E and Hb S, a condition we have not previously seen reported, had a benign clinical course with minor haematological changes, despite a relatively large amount of Hb S (67%).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-5792
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
135-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6437117-Adult,
pubmed-meshheading:6437117-Erythrocytes,
pubmed-meshheading:6437117-Erythrocytes, Abnormal,
pubmed-meshheading:6437117-Genotype,
pubmed-meshheading:6437117-Hemoglobin, Sickle,
pubmed-meshheading:6437117-Hemoglobin E,
pubmed-meshheading:6437117-Hemoglobinopathies,
pubmed-meshheading:6437117-Hemoglobins, Abnormal,
pubmed-meshheading:6437117-Heterozygote,
pubmed-meshheading:6437117-Humans,
pubmed-meshheading:6437117-Infant
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pubmed:year |
1984
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pubmed:articleTitle |
Haemoglobin E variants: a clinical, haematological and biosynthetic study of 4 South African families.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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