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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1984-9-25
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pubmed:abstractText |
Transport of beta-alanine has been demonstrated in membrane vesicles isolated from rat brain, using artificially imposed ion gradients as the sole energy source. The uptake of beta-alanine is strictly dependent on the presence of Na+ and Cl- in the medium, and the process can be driven either by an Na+ gradient (out greater than in) or by a Cl- gradient (out greater than in) when the other essential ion is present. The process is stimulated by a membrane potential (negative inside) as demonstrated by the effect of ionophore valinomycin and anions with different permeabilities. beta-Alanine uptake is inhibited by the presence of GABA.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0364-3190
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
695-707
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6433216-Alanine,
pubmed-meshheading:6433216-Animals,
pubmed-meshheading:6433216-Brain,
pubmed-meshheading:6433216-Cell Membrane,
pubmed-meshheading:6433216-Chlorides,
pubmed-meshheading:6433216-Male,
pubmed-meshheading:6433216-Membrane Potentials,
pubmed-meshheading:6433216-Potassium,
pubmed-meshheading:6433216-Rats,
pubmed-meshheading:6433216-Rats, Inbred Strains,
pubmed-meshheading:6433216-Sodium,
pubmed-meshheading:6433216-Synaptosomes,
pubmed-meshheading:6433216-Time Factors,
pubmed-meshheading:6433216-beta-Alanine,
pubmed-meshheading:6433216-gamma-Aminobutyric Acid
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pubmed:year |
1984
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pubmed:articleTitle |
beta-Alanine transport into plasma membrane vesicles derived from rat brain synaptosomes.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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