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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
|
pubmed:dateCreated |
1984-10-25
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pubmed:abstractText |
Twenty-one cases of newly diagnosed nonlymphocytic leukemia were subjected to analysis of immunoglobulin gene organization. Although immunoglobulin gene organization is an essential property of B-lineage cells, immunoglobulin gene rearrangement has also been observed in mouse T-cells and occasionally in cultured human T-cell leukemic cells. Here we report the first case of acute myelogenous leukemia in which mu-chain gene rearrangement is demonstrated. This finding provides a further step in our understanding of both normal and abnormal hematopoietic cell differentiation and the heterogeneity of nonlymphocytic leukemia.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-5472
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
44
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
4658-60
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6432317-Acute Disease,
pubmed-meshheading:6432317-Adolescent,
pubmed-meshheading:6432317-Adult,
pubmed-meshheading:6432317-B-Lymphocytes,
pubmed-meshheading:6432317-Bone Marrow,
pubmed-meshheading:6432317-Child,
pubmed-meshheading:6432317-Female,
pubmed-meshheading:6432317-Genes,
pubmed-meshheading:6432317-Humans,
pubmed-meshheading:6432317-Immunoglobulin mu-Chains,
pubmed-meshheading:6432317-Immunoglobulins,
pubmed-meshheading:6432317-Leukemia,
pubmed-meshheading:6432317-Leukemia, Myeloid, Acute
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pubmed:year |
1984
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pubmed:articleTitle |
Immunoglobulin gene rearrangement in acute myelogenous leukemia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|