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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1984-7-18
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pubmed:abstractText |
The carbohydrate chains of the pathological human immunoglobulins M from two patients with Waldenström's macroglobulinemia were released by hydrazinolysis. The N-acetyllactosamine-type glycans were obtained by affinity chromatography on concanavalin A and fractionated by high-voltage paper electrophoresis. The primary structure of the major compounds was elucidated on the basis of carbohydrate analysis, methylation analysis, including mass-spectrometry, and 500 MHz 1H-NMR spectroscopy. For both patients, this appeared to be a monosialyl monofucosyl biantennary structure; the compounds differed by the presence of an intersecting N-acetylglucosamine residue.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
170
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6427010-Amino Sugars,
pubmed-meshheading:6427010-Carbohydrate Conformation,
pubmed-meshheading:6427010-Carbohydrate Sequence,
pubmed-meshheading:6427010-Chromatography, Affinity,
pubmed-meshheading:6427010-Electrophoresis, Paper,
pubmed-meshheading:6427010-Humans,
pubmed-meshheading:6427010-Immunoglobulin M,
pubmed-meshheading:6427010-Magnetic Resonance Spectroscopy,
pubmed-meshheading:6427010-Methylation,
pubmed-meshheading:6427010-Polysaccharides,
pubmed-meshheading:6427010-Waldenstrom Macroglobulinemia
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pubmed:year |
1984
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pubmed:articleTitle |
Primary structure of the major glycans of the N-acetyllactosamine type derived from the human immunoglobulins M from two patients with Waldenström's macroglobulinemia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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