| pubmed-article:6425449 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C0021745 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C0040671 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C1521761 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C1515877 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C1516240 | lld:lifeskim |
| pubmed-article:6425449 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:6425449 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:6425449 | pubmed:dateCreated | 1984-6-18 | lld:pubmed |
| pubmed-article:6425449 | pubmed:abstractText | In this report we demonstrate that when the murine macrophage tumor cell line P- 388D1 is incubated for 48-72 h with either concanavalin A-stimulated rat spleen cell supernatant or cloned murine immune interferon (IFN-gamma), the cultured cells release a cell-free factor activity that in turn induces the cell surface expression of Ia antigen on the murine monocyte cell line WEHI-3. This IFN-gamma-stimulated, Ia-inducing activity cannot be blocked with an anti-IFN-gamma heteroantiserum that does block the induction of Ia expression on WEHI-3 by both cloned murine IFN-gamma and rat Con A supernatant. The Ia-inducing factor ( IaIF ) generated from P- 388D1 after stimulation by IFN-gamma does not demonstrate any antiviral activity. The P- 388D1 -derived IaIF is not shed plasma membrane Ia glycoprotein molecules, as demonstrated by the inability of the active component to bind specifically to an anti-I-Ad affinity column or to a protein A column after the active supernatant is first treated with an excess of anti-I-E/Cd,k monoclonal antibody. | lld:pubmed |
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| pubmed-article:6425449 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:6425449 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:6425449 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6425449 | pubmed:month | May | lld:pubmed |
| pubmed-article:6425449 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:6425449 | pubmed:author | pubmed-author:WalkerE BEB | lld:pubmed |
| pubmed-article:6425449 | pubmed:author | pubmed-author:StewartCC | lld:pubmed |
| pubmed-article:6425449 | pubmed:author | pubmed-author:WarnerNN | lld:pubmed |
| pubmed-article:6425449 | pubmed:author | pubmed-author:MainiPP | lld:pubmed |
| pubmed-article:6425449 | pubmed:author | pubmed-author:Sanchez-Lanie... | lld:pubmed |
| pubmed-article:6425449 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6425449 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:6425449 | pubmed:volume | 159 | lld:pubmed |
| pubmed-article:6425449 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6425449 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6425449 | pubmed:pagination | 1532-47 | lld:pubmed |
| pubmed-article:6425449 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6425449 | pubmed:year | 1984 | lld:pubmed |
| pubmed-article:6425449 | pubmed:articleTitle | Murine gamma interferon activates the release of a macrophage-derived Ia-inducing factor that transfers Ia inductive capacity. | lld:pubmed |
| pubmed-article:6425449 | pubmed:publicationType | Journal Article | lld:pubmed |
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