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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1984-4-25
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pubmed:abstractText |
The influence of intravenously administered L-carnitine on lipid- and nitrogen-metabolism was studied during total parenteral nutrition of piglets (mean weight 4077 g; n = 9). The infusion protocol was divided into three isocaloric and isonitrogenous 48-hr periods. Amino acids (3 g/kg day) were administered throughout all three periods: 140 cal/kg/day were given as nonprotein calories, consisting only of glucose during period 1; during periods 2 and 3, an amount of glucose calorically equivalent to 4 g fat/kg/day was substituted with a lipid emulsion, and L-carnitine (1.5 mg/kg/day) was added in period 3. Key parameters of fat- and nitrogen-metabolism were determined during the entire regime. Indirect calorimetry was performed and the respiratory quotient calculated during all three periods. The results demonstrate a more effective lipolysis and oxidation of fatty acids during L-carnitine supplementation. These changes produce an increased energy gain from exogenously administered fat and a distinct improvement in nitrogen balance.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Carnitine,
http://linkedlifedata.com/resource/pubmed/chemical/Fat Emulsions, Intravenous,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Nitrogen
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pubmed:status |
MEDLINE
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pubmed:issn |
0148-6071
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-13
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pubmed:dateRevised |
2007-2-21
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pubmed:meshHeading |
pubmed-meshheading:6422076-Amino Acids,
pubmed-meshheading:6422076-Animals,
pubmed-meshheading:6422076-Calorimetry, Indirect,
pubmed-meshheading:6422076-Carnitine,
pubmed-meshheading:6422076-Fat Emulsions, Intravenous,
pubmed-meshheading:6422076-Glucose,
pubmed-meshheading:6422076-Lipid Metabolism,
pubmed-meshheading:6422076-Lipids,
pubmed-meshheading:6422076-Male,
pubmed-meshheading:6422076-Nitrogen,
pubmed-meshheading:6422076-Oxidation-Reduction,
pubmed-meshheading:6422076-Parenteral Nutrition,
pubmed-meshheading:6422076-Parenteral Nutrition, Total,
pubmed-meshheading:6422076-Swine,
pubmed-meshheading:6422076-Swine, Miniature
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pubmed:articleTitle |
Improved N-retention during L-carnitine-supplemented total parenteral nutrition.
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pubmed:publicationType |
Journal Article
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