rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1984-4-25
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pubmed:abstractText |
A 62-year-old man with clinical and biochemical findings consistent with homozygous Tangier disease is presented. Widespread atherosclerosis was present. Bile lipid analysis showed a low molar percentage of cholesterol with a low saturation index. The data suggest that high density lipoprotein cholesterol may act as a preferential precursor of biliary cholesterol. Coagulation and platelet studies indicated that the patient's platelets were hyper-responsive to aggregating agents and produced an increased amount of thromboxane B2. A platelet storage pool deficiency was also found.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein A-I,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Bile Acids and Salts,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Thromboxane B2
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0014-2972
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
49-54
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6421598-Aged,
pubmed-meshheading:6421598-Apolipoprotein A-I,
pubmed-meshheading:6421598-Apolipoproteins,
pubmed-meshheading:6421598-Bile,
pubmed-meshheading:6421598-Bile Acids and Salts,
pubmed-meshheading:6421598-Blood Coagulation Disorders,
pubmed-meshheading:6421598-Blood Platelet Disorders,
pubmed-meshheading:6421598-Cholesterol,
pubmed-meshheading:6421598-Cholesterol, HDL,
pubmed-meshheading:6421598-Humans,
pubmed-meshheading:6421598-Hypolipoproteinemias,
pubmed-meshheading:6421598-Lipids,
pubmed-meshheading:6421598-Lipoproteins, HDL,
pubmed-meshheading:6421598-Male,
pubmed-meshheading:6421598-Middle Aged,
pubmed-meshheading:6421598-Serotonin,
pubmed-meshheading:6421598-Tangier Disease,
pubmed-meshheading:6421598-Thromboxane B2
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pubmed:year |
1984
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pubmed:articleTitle |
Bile lipid composition and haemostatic variables in a case of high density lipoprotein deficiency (Tangier disease).
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pubmed:publicationType |
Journal Article,
Case Reports
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