|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1984-3-16
|
|
pubmed:abstractText |
The intestinal absorption of dinitrophenyl-lysine (DNP-lys) was studied with a special interest on the role of the immune system in the absorption of small molecules which are recognized as nonself. [3H]-DNP-lys was rapidly absorbed by ligated intestinal loops in situ via a saturable and unique route. When [3H]-DNP-lys was preincubated with the immune serum obtained from rats immunized with dinitrophenylated bovine serum albumin (DNP-BSA), the [3H]-DNP-lys absorption was depressed. The absorption of [3H]-DNP-lys in DNP-BSA-immunized rats was depressed compared to the control. The results obtained suggest that the immune system play a role in avoiding the absorption of small molecules with antigenicity.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0301-4800
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
29
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
563-70
|
|
pubmed:dateRevised |
2003-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:6420526-Animals,
pubmed-meshheading:6420526-Dinitrophenols,
pubmed-meshheading:6420526-Immunization,
pubmed-meshheading:6420526-Intestinal Absorption,
pubmed-meshheading:6420526-Jejunum,
pubmed-meshheading:6420526-Lysine,
pubmed-meshheading:6420526-Male,
pubmed-meshheading:6420526-Rats,
pubmed-meshheading:6420526-Rats, Inbred Strains,
pubmed-meshheading:6420526-Serum Albumin, Bovine,
pubmed-meshheading:6420526-Time Factors
|
|
pubmed:year |
1983
|
|
pubmed:articleTitle |
Intestinal absorption of dinitrophenyl-lysine and effect of immunization with dinitrophenylated bovine serum albumin.
|
|
pubmed:publicationType |
Journal Article
|
