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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1984-2-14
|
| pubmed:abstractText |
The effects of astemizole (10 mg daily for 7 days) on the kinetics and CNS depressant activity of ethanol have been examined in a double-blind cross-over study agonist placebo in 7 volunteers. There was no significant change in the elimination rate or AUC of the plasma ethanol concentration-time curve after astemizole. Central nervous system effects of ethanol as monitored by visual analogues of sedation, visual discrimination, pursuit rotor and reaction time were also unaffected by astemizole pretreatment.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0031-6970
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
567-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6418551-Adult,
pubmed-meshheading:6418551-Astemizole,
pubmed-meshheading:6418551-Benzimidazoles,
pubmed-meshheading:6418551-Double-Blind Method,
pubmed-meshheading:6418551-Drug Interactions,
pubmed-meshheading:6418551-Ethanol,
pubmed-meshheading:6418551-Humans,
pubmed-meshheading:6418551-Kinetics,
pubmed-meshheading:6418551-Male,
pubmed-meshheading:6418551-Middle Aged,
pubmed-meshheading:6418551-Psychomotor Performance
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Lack of effect of astemizole on ethanol dynamics or kinetics.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|