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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1984-1-26
|
| pubmed:abstractText |
The binding studies in this paper indicate that the catalytic unit(s) of microsomal UDP glucuronosyltransferase(s) is not accessible to N-ethylmaleimide or UDP-N-acetylglucosamine, when the enzyme is in its membrane environment. Thus a separate regulatory factor may exist within the endoplasmic reticulum membrane that mediates the stimulation of UDPglucuronosyltransferase(s) by UDP-N-acetylglucosamine. The possible role and the mode of interaction of the putative regulatory factor with the multiple forms of UDPglucuronosyltransferase are discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0006-3002
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
23
|
| pubmed:volume |
735
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
309-13
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6416295-Animals,
pubmed-meshheading:6416295-Electrophoresis, Disc,
pubmed-meshheading:6416295-Endoplasmic Reticulum,
pubmed-meshheading:6416295-Ethylmaleimide,
pubmed-meshheading:6416295-Glucuronosyltransferase,
pubmed-meshheading:6416295-Intracellular Membranes,
pubmed-meshheading:6416295-Microsomes, Liver,
pubmed-meshheading:6416295-Rats,
pubmed-meshheading:6416295-Uridine Diphosphate N-Acetylglucosamine,
pubmed-meshheading:6416295-Uridine Diphosphate Sugars
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Evidence indicating that UDP-N-acetylglucosamine does not appear to stimulate hepatic microsomal UDP-glucuronosyltransferase by interaction with the catalytic unit of the enzyme.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|