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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1983-12-17
|
| pubmed:abstractText |
Gel filtration (sepharose 2B CL) patterns of factor VIII coagulant antigen (VIIIC:Ag) and factor VIII related antigen (VIIIR:Ag) were obtained using normal plasma and plasma from patients with von Willebrand's disease. The latter group consisted of five individuals with normal mobility of factor VIIIR:Ag on cross-immunoelectrophoresis (Type I) and five others with abnormal (increased) mobility (Type II). Results showed that the elution of VIIIC:Ag was delayed in those subjects whose ratio of VIIIR:Ag to VIIIC:Ag was reduced. It has previously been reported that VIIIR:Ag exerts a stabilizing influence on the coagulant activity of factor VIII (VIII:C); our data suggests that when VIIIR:Ag is deficient, abnormal (low molecular weight) forms of VIIIC:Ag circulate.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0340-6245
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
30
|
| pubmed:volume |
50
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
509-12
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:6415844-Antigens,
pubmed-meshheading:6415844-Chromatography, Gel,
pubmed-meshheading:6415844-Cross Reactions,
pubmed-meshheading:6415844-Factor VIII,
pubmed-meshheading:6415844-Hemophilia A,
pubmed-meshheading:6415844-Humans,
pubmed-meshheading:6415844-Immunoelectrophoresis, Two-Dimensional,
pubmed-meshheading:6415844-Molecular Weight,
pubmed-meshheading:6415844-von Willebrand Diseases,
pubmed-meshheading:6415844-von Willebrand Factor
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Gel filtration patterns of factor VIII coagulant antigen and factor VIII related antigen in normal and von Willebrand's disease.
|
| pubmed:publicationType |
Journal Article
|