Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-12-17
pubmed:abstractText
An assay is described for the simultaneous determination of the deaminated metabolites 3,4-dihydroxyphenylethylene glycol (DHPG) and 3,4-dihydroxyphenylacetic acid (DOPAC), together with noradrenaline, dopamine and adrenaline in brain using high performance liquid chromatography with electrochemical detection. The procedure is simple, specific, and has a limit of detection for each catechol of 5 pg. It offers the advantage of measuring the major monoamine oxidase metabolites of both noradrenaline (i.e. DHPG) and dopamine (i.e. DOPAC), which in some circumstances may reflect neuronal activity, simultaneously with their catecholamine neurotransmitter precursors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-32
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:6415553-3,4-Dihydroxyphenylacetic Acid, pubmed-meshheading:6415553-Animals, pubmed-meshheading:6415553-Brain, pubmed-meshheading:6415553-Brain Chemistry, pubmed-meshheading:6415553-Catecholamines, pubmed-meshheading:6415553-Chromatography, High Pressure Liquid, pubmed-meshheading:6415553-Cold Temperature, pubmed-meshheading:6415553-Dopamine, pubmed-meshheading:6415553-Droxidopa, pubmed-meshheading:6415553-Electrochemistry, pubmed-meshheading:6415553-Epinephrine, pubmed-meshheading:6415553-Female, pubmed-meshheading:6415553-Kinetics, pubmed-meshheading:6415553-Norepinephrine, pubmed-meshheading:6415553-Phenylacetates, pubmed-meshheading:6415553-Physical Exertion, pubmed-meshheading:6415553-Rats, pubmed-meshheading:6415553-Rats, Inbred Strains, pubmed-meshheading:6415553-Serine
pubmed:year
1983
pubmed:articleTitle
The simultaneous determination of 3,4-dihydroxyphenyl-ethylene glycol, 3,4-dihydroxyphenylacetic acid and catecholamines in brain tissue by high performance liquid chromatography with electrochemical detection.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't