Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1983-12-20
pubmed:abstractText
A 39-year-old female with scleroderma was maintained on total parenteral nutrition (TPN) at home for four years. She received 2 units of a 10% fat emulsion per week in which 55% of the fatty acids were from linoleate and 7% from linolenate. She was initially placed on TPN because she had difficulty in swallowing due to scleroderma. At the end of four years she had a triene:tetraene ratio of greater than 1. There was evidence of alterations in membrane function due to essential fatty acid deficiency including CNS involvement (blindness, impaired hearing and disorientation) as well as respiratory insufficiency. The diagnosis of membrane involvement was made from gas chromatography (gc) and gc-mass spectroscopy (ms) analysis of red cell membranes which were deficient in linoleate. The patient's immediate cause of death was from respiratory insufficiency.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0731-5724
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
241-7
pubmed:dateRevised
2008-6-23
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Linoleate and possibly linolenate deficiency in a patient on long-term intravenous nutrition at home.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Case Reports