Linked Life Data

6414396

Source:http://linkedlifedata.com/resource/pubmed/id/6414396

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-11-23
pubmed:abstractText
The effects of N-Ac-D-p-F-Phe1,D-p-Cl-Phe2,D-Trp3,6,D-Ala10-LH-RH, a new antagonistic analog of LH-RH, were tested on the testicular function and serum FSH and LH levels in immature male rats. Prolonged administration of this analog to prepubertal male rats resulted in lower testicular and seminal vesicle weights as compared with control rats treated with the vehicle only. Spermatogenesis was markedly delayed in rats injected with the analog. Serum FSH and LH levels were significantly lower in the analog-treated rats as compared to the controls. These data show that LH-RH antagonists may be useful for inhibition of spermatogenesis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0148-5016
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-93
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effect of a powerful antagonist of LH-RH on testicular function in prepubertal male rats.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.