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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1983-11-23
|
| pubmed:abstractText |
ApoA-I is the major apolipoprotein component of human high density lipoproteins (HDL). By a 2-D electrophoretic study of serum samples from Norwegian families, an apoA-I variant (apoA-I 2-1) was detected in a healthy individual. In the present study performed to elucidate formal and population genetic aspects of apoA-I, this variant was observed in 4 generations of the family of the propositus. One homozygous individual was found. A codominant autosomal Mendelian inheritance was established for the variant. Two heterozygotes were found among 124 unrelated individuals tested. The apoA-I 2 allele frequency was calculated as 0.008 in this population sample.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0340-6717
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
64
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
380-3
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:6413385-Apolipoprotein A-I,
pubmed-meshheading:6413385-Apolipoproteins,
pubmed-meshheading:6413385-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:6413385-Female,
pubmed-meshheading:6413385-Gene Frequency,
pubmed-meshheading:6413385-Genes, Dominant,
pubmed-meshheading:6413385-Genetic Variation,
pubmed-meshheading:6413385-Heterozygote,
pubmed-meshheading:6413385-Homozygote,
pubmed-meshheading:6413385-Humans,
pubmed-meshheading:6413385-Lipoproteins, HDL,
pubmed-meshheading:6413385-Male,
pubmed-meshheading:6413385-Norway,
pubmed-meshheading:6413385-Pedigree
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Genetic studies of an apoA-I lipoprotein variant.
|
| pubmed:publicationType |
Journal Article
|