rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
1983-10-28
|
pubmed:abstractText |
The complement-fixing activity, specificity for IgG, and cross-idiotypes of rheumatoid factors (RF) isolated from the mixed cryoglobulins of nine patients with idiopathic mixed cryoglobulinemia were determined. All were IgM kappa and fixed complement. The RF complement-fixing activity did not correlate with hypocomplementemia or disease manifestations. The majority of RF belonged to the same cross-idiotype group. The RF from two of three patients with predominantly neurologic manifestations did not have any of the known cross-idiotypes and reacted better with rabbit IgG than with human IgG. The patients with neurologic manifestations also differed in that their serum complement was normal.
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pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0090-1229
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
29
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
146-51
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:6411403-Adult,
pubmed-meshheading:6411403-Aged,
pubmed-meshheading:6411403-Complement Activation,
pubmed-meshheading:6411403-Complement System Proteins,
pubmed-meshheading:6411403-Cryoglobulinemia,
pubmed-meshheading:6411403-Female,
pubmed-meshheading:6411403-Humans,
pubmed-meshheading:6411403-Immunoglobulin G,
pubmed-meshheading:6411403-Immunoglobulin Idiotypes,
pubmed-meshheading:6411403-Immunoglobulin M,
pubmed-meshheading:6411403-Immunoglobulin kappa-Chains,
pubmed-meshheading:6411403-Middle Aged,
pubmed-meshheading:6411403-Paraproteinemias,
pubmed-meshheading:6411403-Rheumatoid Factor
|
pubmed:year |
1983
|
pubmed:articleTitle |
Characterization of complement-fixing activity and cross-idiotypes of rheumatoid factors in idiopathic mixed cryoglobulinemia.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|