Linked Life Data

6411050

Source:http://linkedlifedata.com/resource/pubmed/id/6411050

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1983-9-9
pubmed:abstractText
Mixtures of carbon dioxide and oxygen are commonly used in the treatment of central retinal artery obstruction to improve retinal oxygenation. While oxygen alone causes retinal vasoconstriction, it is thought that the carbon dioxide balances this effect, even causing a net vasodilatation. To test this hypothesis, normal, healthy volunteers were given 100% oxygen, a mixture of 95% oxygen and 5% carbon dioxide, and a mixture of 5% carbon dioxide in air to breathe. The caliber of large, fluorescein-filled retinal arteries and veins was then measured using computer processing of digitized television images. The marked decrease in arterial and venous caliber caused by 100% oxygen was not reversed by the subsequent addition of 5% carbon dioxide. Moreover, 5% carbon dioxide in air did not cause substantial vasodilatation of the retinal vasculature. The efficacy of adding 5% carbon dioxide to oxygen to treat retinal vascular obstructive diseases is questioned.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0003-9950
pubmed:author
pubmed:issnType
Print
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1278-80
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Effects of oxygen and carbon dioxide on the retinal vasculature in humans.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't