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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4612
|
pubmed:dateCreated |
1983-9-20
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pubmed:databankReference | |
pubmed:abstractText |
Ia (I region-associated) antigens are cell-surface glycoproteins involved in the regulation of immune responsiveness. They are composed of one heavy (alpha) and one light (beta) polypeptide chain. We have sequenced the gene encoding the A beta d chain of the BALB/c mouse. The presence of six exons is predicted by comparison with the complementary DNA sequences of human beta chains and with partial protein sequence data for the A beta d polypeptide. Sequence comparisons have been made to other proteins involved in immune responses and the consequent implications for the evolutionary relationships of these genes are discussed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0036-8075
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
19
|
pubmed:volume |
221
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
750-4
|
pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:6410508-Animals,
pubmed-meshheading:6410508-Base Sequence,
pubmed-meshheading:6410508-Biological Evolution,
pubmed-meshheading:6410508-Codon,
pubmed-meshheading:6410508-Genes,
pubmed-meshheading:6410508-Genes, MHC Class II,
pubmed-meshheading:6410508-Macromolecular Substances,
pubmed-meshheading:6410508-Major Histocompatibility Complex,
pubmed-meshheading:6410508-Mice,
pubmed-meshheading:6410508-beta 2-Microglobulin
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pubmed:year |
1983
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pubmed:articleTitle |
Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|