Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-8-17
pubmed:abstractText
The literature on quantitation of immunoglobulins in normal CSF and variations of these values related to race, sex and age was reviewed. Immunoglobulins (Ig) G, A and M of normal CSF (sub-occipital puncture) of 116, 78 and 45 patients respectively, were measured by radial immunodiffusion, in order to verify variations related to race, sex and age, as well as to establish their normal limits. The results allowed us to conclude that: a) there are no differences between races with respect to the levels of IgG, A and M; b) variations related to sex or age on the CFS immunoglobulins content in children (1 to 11 years old) are not found; c) the mean IgG (mg/100 ml) level in children is lower than in adults, although the mean IgG percentage concentration in children is not different from that found in adults; the normal range for CSF IgG in children is 0.21 to 2.93 mg/100 ml; d) the mean IgA content (mg/100 ml and % of the total protein) in children are lower than in adults and in physiological conditions do not exceed 0.15 mg/100 ml (0.7% of the total protein); e) there are no differences related to sex or age with respect to the CSF levels of immunoglobulins in adults; the normal range of IgG in adults is 0.51 to 4.00 mg/100 ml; in children and adults the normal limits for the relative values of IgG are 3 to 12%; IgA is found in the CFS of adults in a concentration up to 0.32 mg/100 ml (0.9%); f) IgM is found in both children's and adults' CSF at very low levels, not exceeding 0.2 mg/100 ml (0.25%). Comparison of the results obtained in this work with those found in some publications was carried out and is briefly discussed.
pubmed:language
por
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0004-282X
pubmed:author
pubmed:issnType
Print
pubmed:volume
41
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
25-49
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Cerebrospinal fluid proteins: III. Normal values of immunoglobulins G, A and M (variations related to race, sex and age)].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract