Linked Life Data

6408602

Source:http://linkedlifedata.com/resource/pubmed/id/6408602

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-8-11
pubmed:abstractText
Coupling of salt and water movements across kidney proximal tubules was studied in the presence of an induced transepithelial osmotic water flux. Convoluted proximal tubules from rabbit kidney were perfused in vitro with a control solution, with or without 50 mM/l of mannitol or raffinose in the both. Osmolalities of the perfused and collected fluids as well as the net water flux Jv were measured in each experiment. The net solute flux Js was calculated from the difference between the amount of total solutes delivered and collected at each end of the tubule. No apparent net transepithelial solute movements were detected in the presence of an osmotic water flux when active solute transport was inhibited either by an external to of 26 degrees C or by ouabain in the bath. The water flux observed was similar to that calculated assuming that only water crossed the epithelium, and no streaming potential was measured, whether or not active transport was blocked. It is concluded that the osmotic water flux through kidney proximal tubule does not drag a significant amount of solutes, probably because of the absence of convective solvent flux. This suggests the existence of different pathways for water and salt movement.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0031-6768
pubmed:author
pubmed:issnType
Print
pubmed:volume
397
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
35-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Does water drag solutes through kidney proximal tubule?
pubmed:publicationType
Journal Article, In Vitro