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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6380
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pubmed:dateCreated |
1983-8-11
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pubmed:abstractText |
Use of monoclonal antibodies to identify subpopulations of circulating lymphocytes in healthy adults showed pronounced circadian variations in total T cells, the two major T cell subsets, and HLA-DR+ lymphocytes. When the results for the T cell subsets were expressed as a ratio (helper:suppressor) no significant rhythmic variation was observed. Lymphocytes bearing a surface antigen identified by the HNK-1 antibody (a population containing the natural killer and antibody dependent killer activity) did not show significant rhythmic variation. There was an inverse relation between plasma cortisol concentration and numbers of T and B cells. These observations have therapeutic implications and should be considered in the course of immunological monitoring.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-11344571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-13969762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-310741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-39699,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-4566775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-4808638,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-548245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-56007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-6221840,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-6446683,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-6454075,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-6790607,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-6980948,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6407561-7108226
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0267-0623
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
4
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pubmed:volume |
286
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1773-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6407561-Adult,
pubmed-meshheading:6407561-Antibodies, Monoclonal,
pubmed-meshheading:6407561-B-Lymphocytes,
pubmed-meshheading:6407561-Circadian Rhythm,
pubmed-meshheading:6407561-Humans,
pubmed-meshheading:6407561-Hydrocortisone,
pubmed-meshheading:6407561-Leukocyte Count,
pubmed-meshheading:6407561-Lymphocytes,
pubmed-meshheading:6407561-Middle Aged,
pubmed-meshheading:6407561-T-Lymphocytes
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pubmed:year |
1983
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pubmed:articleTitle |
Circadian variation of lymphocyte subpopulations: a study with monoclonal antibodies.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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