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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-7-8
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pubmed:abstractText |
Monoclonal antibodies with specificities for subsets of human leukocytes have been used for the characterization of interferon (IFN) gamma-producing cells. The production of IFN gamma was demonstrated to be a function of OKT3+T lymphocytes. The capacity to secrete IFN gamma was not restricted to the OKT4+ or the OKT8+T-cell subset. BA-1+B lymphocytes and Leu7+ natural killer cells did not contribute to the production of IFN gamma. Ia+, OKM1+ monocytes served an auxiliary function in the production of IFN gamma. The requirement for accessory monocytes, however, was not absolute, because monocyte-free preparations of long-term cultured IL2-dependent T lymphocytes retained the capacity to secrete IFN gamma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0300-8584
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
171
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
215-23
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:6406805-Antibodies, Monoclonal,
pubmed-meshheading:6406805-Humans,
pubmed-meshheading:6406805-Interferon-gamma,
pubmed-meshheading:6406805-Interleukin-2,
pubmed-meshheading:6406805-Killer Cells, Natural,
pubmed-meshheading:6406805-Leukocytes,
pubmed-meshheading:6406805-T-Lymphocytes
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pubmed:year |
1983
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pubmed:articleTitle |
Characterization of human interferon-gamma-producing leukocytes with monoclonal antileukocyte antibodies.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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