Linked Life Data

6406457

Source:http://linkedlifedata.com/resource/pubmed/id/6406457

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5 Pt 2
pubmed:dateCreated
1983-7-8
pubmed:abstractText
The incidence of convulsions in patients receiving tricyclic antidepressants or bupropion was reviewed. For both types of drug, the risk of a seizure was dose-dependent and was higher in patients with predisposing factors, e.g., a history of seizures. Patients without a predisposing factor had a convulsion incidence of approximately 0.6%-0.9% (6-9/1,000 patients) when receiving imipramine at doses of greater than 200 mg/day or bupropion at doses greater than 450 mg/day. At lower doses, the frequency of seizures dropped to about 1/1,000 (or less) for imipramine and bupropion. Thus, the risk of a seizure in patients receiving equally therapeutic doses of imipramine and bupropion appears to be comparable.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0160-6689
pubmed:author
pubmed:issnType
Print
pubmed:volume
44
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-201
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Incidence of seizures during treatment with tricyclic antidepressant drugs and bupropion.
pubmed:publicationType
Journal Article, Comparative Study, Review