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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1983-7-8
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pubmed:abstractText |
The results of radiation therapy as applied to patients with squamous cell carcinoma of the hypopharynx seen during the period 1972-1976 at the Princess Margaret Hospital are presented. Approximately 2/3 of the patient population presented with disease involving the regional lymph nodes or with systemic metastases. Ninety percent (127/141) of all patients registered were treated primarily with radiation therapy with surgery reserved for the management of residual or recurrent disease only. Seventy-seven percent (98/127) of those who received radiation therapy were treated with radical intent. The uncorrected actuarial 5 year survival rate for those patients treated radically was 19%. Five year actuarial survival rates by the UICC TNM (1974) staging system, showed that nodal disease was the most significant determinant of survival. Five year survival rates were as follows: N0 36%; N1 20%; N2N30%. When considered within each nodal category the survival of the combined T1T2 group was not significantly different from the T3 category. Forty-five percent of those patients who failed with local or regional disease had an attempt at salvage surgery. Of these, 6/24 ultimately achieved local and regional control. Comparisons with other series in the literature are discussed and reasons for differences in published results are considered.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
659-64
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6406405-Carcinoma, Squamous Cell,
pubmed-meshheading:6406405-Cobalt Radioisotopes,
pubmed-meshheading:6406405-Female,
pubmed-meshheading:6406405-Humans,
pubmed-meshheading:6406405-Hypopharynx,
pubmed-meshheading:6406405-Male,
pubmed-meshheading:6406405-Middle Aged,
pubmed-meshheading:6406405-Pharyngeal Neoplasms,
pubmed-meshheading:6406405-Radiotherapy, High-Energy,
pubmed-meshheading:6406405-Retrospective Studies
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pubmed:year |
1983
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pubmed:articleTitle |
Carcinoma of the hypopharynx results of primary radical radiation therapy.
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pubmed:publicationType |
Journal Article
|