Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6379
pubmed:dateCreated
1983-7-29
pubmed:abstractText
A computer program incorporating an adaptation of a statistical method, the multiprocess Kalman filter, was used to detect changes in trends of plasma creatinine and urea concentrations. In 28 recipients of renal allografts a definite deterioration in renal function was identified retrospectively on 32 occasions by an experienced renal physician independently of the statistical analysis. The computer identified 31 of these 32 episodes using creatinine and urea results, and 29 using creatinine alone. Dysfunction was identified by the computer significantly earlier (p less than 0.05) than by the clinician and a median of one day earlier (p less than 0.02) than treatment was actually initiated. The computer identified dysfunction on 11 out of 1259 days when the clinician did not suspect rejection. These 11 episodes may have had a pathological importance, though no clinical diagnosis was made. This computer method is useful for immediate analysis of incoming results and for timing events either prospectively or retrospectively.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-367500, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-385207, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-428215, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-438712, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-445835, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-6115199, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-63803, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-6454075, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-69100, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-7036176, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-7407311, http://linkedlifedata.com/resource/pubmed/commentcorrection/6405938-839654
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0267-0623
pubmed:author
pubmed:issnType
Print
pubmed:day
28
pubmed:volume
286
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1695-9
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Detection of renal allograft rejection by computer.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't