Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1983-6-17
|
pubmed:abstractText |
Nine clinical isolates of Streptococcus faecalis from a university hospital were found to be resistant to high levels (minimal inhibitory concentration, greater than 2,000 micrograms/ml) of gentamicin, tobramycin, amikacin, streptomycin, and kanamycin. The high-level resistance to these aminoglycosides and resistance to penicillin-aminoglycoside synergism were transferable by conjugation to a susceptible recipient strain. In three strains tested, the aminoglycoside resistance was mediated by four aminoglycoside-modifying enzymes: a 3'-phosphotransferase transferred from two strains, a 2"-phosphotransferase and a 6'-acetyltransferase transferred from all three strains, and a streptomycin adenylyltransferase transferred from two strains. This is the first report of the occurrence of high-level gentamicin resistance in enterococcal isolates from the United States.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0022-1899
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
147
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
751-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6404994-Aminoglycosides,
pubmed-meshheading:6404994-Anti-Bacterial Agents,
pubmed-meshheading:6404994-Conjugation, Genetic,
pubmed-meshheading:6404994-Drug Resistance, Microbial,
pubmed-meshheading:6404994-Drug Synergism,
pubmed-meshheading:6404994-Enterococcus faecalis,
pubmed-meshheading:6404994-Gentamicins,
pubmed-meshheading:6404994-Hospitals, University,
pubmed-meshheading:6404994-Microbial Sensitivity Tests,
pubmed-meshheading:6404994-R Factors,
pubmed-meshheading:6404994-Transferases,
pubmed-meshheading:6404994-United States
|
pubmed:year |
1983
|
pubmed:articleTitle |
High-level resistance to gentamicin in clinical isolates of enterococci.
|
pubmed:publicationType |
Journal Article
|