| pubmed-article:6404440 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C0062527 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C0242658 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C0008976 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C0013072 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C1274040 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C0018837 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:6404440 | lifeskim:mentions | umls-concept:C1696465 | lld:lifeskim |
| pubmed-article:6404440 | pubmed:issue | 6374 | lld:pubmed |
| pubmed-article:6404440 | pubmed:dateCreated | 1983-6-10 | lld:pubmed |
| pubmed-article:6404440 | pubmed:abstractText | The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a randomised placebo controlled double blind trial. At the trial end point (21.5 months), 17 hepatitis B virus infections had occurred in vaccinated subjects (attack rate 4.8%) and 56 in subjects receiving a placebo (attack rate 23.8%). This reduction in the incidence of hepatitis B virus infections in vaccinated subjects was highly significant (p less than 0.0001). Two months after the first injection 72.3% of the vaccinated subjects had formed antibodies against hepatitis B surface antigen, and this percentage increased to 89% at four months. Maximum anti-HBs titres were reached five months after the first vaccination, the geometric mean titre being 107.6 mIU. Even vaccinated subjects with a low antibody response (greater than or equal to 1 and less than 10 mIU) were found to be protected from HBsAg-positive infections. The vaccine had no serious side effects. | lld:pubmed |
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| pubmed-article:6404440 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:6404440 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:6404440 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6404440 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:6404440 | pubmed:issn | 0267-0623 | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:HuismanJJ | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:ReesinkH WHW | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:Reerink-Brong... | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:CoutinhoR ARA | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:StoutjesdijkL... | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:NivardJJ | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:LelieNN | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:Albrecht-Van... | lld:pubmed |
| pubmed-article:6404440 | pubmed:author | pubmed-author:DeesPP | lld:pubmed |
| pubmed-article:6404440 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6404440 | pubmed:day | 23 | lld:pubmed |
| pubmed-article:6404440 | pubmed:volume | 286 | lld:pubmed |
| pubmed-article:6404440 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6404440 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6404440 | pubmed:pagination | 1305-8 | lld:pubmed |
| pubmed-article:6404440 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:6404440 | pubmed:year | 1983 | lld:pubmed |
| pubmed-article:6404440 | pubmed:articleTitle | Efficacy of a heat inactivated hepatitis B vaccine in male homosexuals: outcome of a placebo controlled double blind trial. | lld:pubmed |
| pubmed-article:6404440 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6404440 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:6404440 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:6404440 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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