Linked Life Data

640272

Source:http://linkedlifedata.com/resource/pubmed/id/640272

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1978-6-12
pubmed:abstractText
This study describes an in vitro experimental model of the sphincter at the lower end of the main pancreatic duct in the dog. This model, employing a drop counter to measure the drop rate, monitors the perfusion rate of Tyrode through the sphincter. Acetylcholine (ACh), employed to establish the sensitivity and viability of the isolated sphincter, produced a contraction of the sphincter which was concentration-response related. Saline, as a control, atropine and hexamethonium did not affect the drop rate. Atropine (20 microgram) partially abolished the contraction produced by 50 microgram of ACh; hexamethonium (50 microgram) did not have an effect. Caerulein 50 microgram produced a relaxation of the sphincter; adrenaline 50 microgram a contraction. Both sympathetic and parasympathetic mechanisms seem to play a role in the regulation of sphincteric activity of the main pancreatic duct in dogs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0012-2823
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
Sphincteric mechanism of the main pancreatic duct in the dog. An experimental model of the isolated sphincteric preparation.
pubmed:publicationType
Journal Article