Linked Life Data

6401957

Source:http://linkedlifedata.com/resource/pubmed/id/6401957

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1983-3-17
pubmed:abstractText
Cell-mediated immunity was evaluated in 26 patients with sickle cell anemia using skin tests for delayed hypersensitivity reactions. Patients with impaired delayed hypersensitivity reactions had lower zinc levels in plasma, erythrocytes, and neutrophils than patients with normal delayed hypersensitivity reactions or controls. The activity of nucleoside phosphorylase, an enzyme essential for T-lymphocyte function, was significantly lower in zinc-deficient patients with anergic sickle cell anemia. We conclude that zinc deficiency in patients with sickle cell anemia is associated with impaired delayed hypersensitivity. Decreased activity of nucleoside phosphorylase may be partially responsible for lymphocyte dysfunction in these patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0003-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
98
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
180-2
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Anergy, zinc deficiency, and decreased nucleoside phosphorylase activity in patients with sickle cell anemia.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't