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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1983-2-25
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pubmed:abstractText |
Progressive muscle weakness in acid maltase deficiency (AMD) is associated with intralysosomal accumulation of glycogen and altered myofibrillar morphology. A rapid fall in circulating branched chain amino acids after protein ingestion in a child with AMD suggested that increased net muscle protein catabolism may play a part in the pathogenesis of this condition. To reduce this muscle catabolism, the patient was treated with a high-protein diet for 12 months. This has reversed the weakness and wasting, with improvement in muscle function, exercise tolerance, and growth.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0028-3878
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
34-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6401355-Amino Acids, Branched-Chain,
pubmed-meshheading:6401355-Child, Preschool,
pubmed-meshheading:6401355-Dietary Proteins,
pubmed-meshheading:6401355-Glucan 1,4-alpha-Glucosidase,
pubmed-meshheading:6401355-Glucosidases,
pubmed-meshheading:6401355-Glycogen,
pubmed-meshheading:6401355-Humans,
pubmed-meshheading:6401355-Male,
pubmed-meshheading:6401355-Muscles,
pubmed-meshheading:6401355-Muscular Diseases
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pubmed:year |
1983
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pubmed:articleTitle |
Improvement of muscle function in acid maltase deficiency by high-protein therapy.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports,
Research Support, Non-U.S. Gov't
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