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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1990-6-6
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pubmed:abstractText |
Four different molecular weight forms of the Ly-5 antigen were defined by immunochemical methods on the cell surface of murine spleen cells using a monoclonal antibody. Each form was selectively expressed by cells belonging to different lineages. A 220,000-dalton molecule was associated with B cells, a 200,000-dalton molecule with macrophages and two antigens of 185,000 and 175,000 daltons, respectively, were detected on the cell surface of normal thymocytes. The 185,000-dalton Ly-5 molecule was not found on the lymphoid cells of immunodeficient mice, like the athymic nude or the athymic-asplenic (LASAT) mice, suggesting that cells bearing this Ly-5 molecule have a significant function in some T-dependent immune responses.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0254-9670
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
1
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6400994-Animals,
pubmed-meshheading:6400994-Antigens, Ly,
pubmed-meshheading:6400994-Antigens, Neoplasm,
pubmed-meshheading:6400994-Immunologic Deficiency Syndromes,
pubmed-meshheading:6400994-Lymphoma,
pubmed-meshheading:6400994-Mice,
pubmed-meshheading:6400994-Mice, Inbred Strains,
pubmed-meshheading:6400994-Mice, Mutant Strains,
pubmed-meshheading:6400994-Mice, Nude,
pubmed-meshheading:6400994-Molecular Weight,
pubmed-meshheading:6400994-Spleen,
pubmed-meshheading:6400994-T-Lymphocytes,
pubmed-meshheading:6400994-Thymus Gland
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pubmed:year |
1984
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pubmed:articleTitle |
Ly-5 molecular forms in congenitally immunodeficient mice.
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pubmed:affiliation |
Division of Experimental Oncology A, National Tumor Institute, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|