Linked Life Data

6399465

Source:http://linkedlifedata.com/resource/pubmed/id/6399465

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
1985-10-10
pubmed:abstractText
There are good reasons to believe that adhesion of particulate matter in all wet, salty, biochemically active circumstances follows a common pattern, and that such adhesion can be effectively controlled by adjusting the surface properties - especially surface energy--of the substrate involved. One of the most compelling proofs of, at least, the bioengineering utility of surface energy modification to maximize or minimize biological adhesion is the successful, now long-term, implantation of total artificial hearts. These pumps, and the related intra-aortic balloons and left ventricular assist devices, do not accumulate blood clots or thrombotic masses during their contact with natural blood. Since surfaces contacting blood have received most careful scrutiny for more than a decade, the instruction gained from examining the usual and unusual sequelae of blood cell adhesion to nonphysiologic surfaces has been most valuable in revealing the general features of biological adhesion in other, less well-studied, circumstances. The initial events of blood contact with foreign solid surfaces are briefly reviewed, and the impressive similarities of these events to sequences in oceanic fouling of heat exchangers, cell culture experiments and dental plaque formation are highlighted. A unifying concept, based on control of the surface free energy through an empirical correlate called the "critical surface tension," is presented as an explanation for the common features of biological adhesion in all of Nature's domains.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0090-5488
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
133-59
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Adhesion in the biologic environment.
pubmed:publicationType
Journal Article