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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2-4
|
| pubmed:dateCreated |
1985-5-31
|
| pubmed:abstractText |
M. leprae produced concentration-dependent bimodal effects in cultures of M. leprae-immune lymphocytes. At low to intermediate concentrations, M. leprae and other species of mycobacteria stimulated lymphoproliferation of M. Leprae T-helper cell clones, whereas at high concentrations responses were reduced. Lymphokine production by M. leprae-immune T-cell hybridomas also showed bimodal responses to different concentrations of M. leprae. These results indicate that mycobacterial antigen may directly induce tolerance of responsing lymphocytes.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0001-5938
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
369-77
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:6398595-Animals,
pubmed-meshheading:6398595-Clone Cells,
pubmed-meshheading:6398595-Hybridomas,
pubmed-meshheading:6398595-Interleukin-2,
pubmed-meshheading:6398595-Lymphokines,
pubmed-meshheading:6398595-Macrophage-Activating Factors,
pubmed-meshheading:6398595-Mice,
pubmed-meshheading:6398595-Mice, Inbred BALB C,
pubmed-meshheading:6398595-Mycobacterium leprae,
pubmed-meshheading:6398595-T-Lymphocytes,
pubmed-meshheading:6398595-Thymidine
|
| pubmed:articleTitle |
Concentration-dependent effects of mycobacteria on the stimulation of murine T-cell clones.
|
| pubmed:publicationType |
Journal Article
|